Which of the following is a potential adverse effect of dextran use for volume expansion?

Dextran is a colloid solution commonly used for volume expansion in clinical settings, particularly in cases of shock or significant blood loss. Its mechanism involves increasing the osmotic pressure within the vascular compartment, thereby drawing fluid into the circulation and improving cardiac output and perfusion.

One of the notable adverse effects associated with dextran is the potential for anaphylaxis. Anaphylactic reactions can occur due to hypersensitivity to dextran or components involved in its formulation. Symptoms of anaphylaxis may include urticaria, angioedema, respiratory distress, and cardiovascular collapse. This potential reaction underscores the importance of monitoring patients closely after administration, particularly if there is a history of allergies to similar products.

While volume overload can be a concern with any volume expander, particularly if administered in excessive quantities or in patients with compromised renal function or heart failure, it does not specifically relate to dextran's unique risk factors like anaphylaxis does. Hypotension is less common and would usually be an unlikely immediate reaction, while visual disturbances are not typically associated with dextran either.

Understanding the risk of anaphylaxis as a serious adverse effect emphasizes the need to weigh the benefits of dextran administration against its potential complications, particularly in patients who may be at higher