What is the therapeutic range for magnesium sulfate in the treatment of preeclampsia?

The therapeutic range for magnesium sulfate in the treatment of preeclampsia is indeed 4 to 7 mEq/L. This range is established to effectively manage and prevent seizures associated with the condition. Magnesium sulfate acts as a central nervous system depressant, helping to stabilize neuronal excitability and thus reducing the likelihood of seizures.

When magnesium sulfate levels are maintained within this therapeutic range, it provides optimal benefits for patients while minimizing the risk of adverse effects that can occur if levels are too low or too high. Levels below 4 mEq/L may not confer adequate seizure prophylaxis, while levels above 7 mEq/L can lead to toxicity, characterized by symptoms such as respiratory depression, loss of deep tendon reflexes, and cardiac complications.

Understanding this range is crucial for healthcare providers as it guides the administration and monitoring of treatment to ensure patient safety and effective management of preeclampsia.