What happens to uterine blood flow at term compared to the nonpregnant state?

During pregnancy, particularly by term, there is a significant increase in uterine blood flow, which is necessary to support the growing fetus and the ongoing demands of the placenta. At term, uterine blood flow is estimated to approximately double compared to the nonpregnant state.

This increase is primarily due to the physiological changes that occur during pregnancy, including adaptations in maternal cardiovascular function, such as increased blood volume and cardiac output. These adaptations allow for enhanced perfusion to the uterus, which is vital for supplying oxygen and nutrients to the developing fetus.

In terms of specific numbers, uterine blood flow can reach values of 600-800 mL/min at term, compared to about 50 mL/min in a nonpregnant state. This marked increase facilitates the needs of the placenta and supports fetal growth and development.

The other options indicate lower levels of blood flow, which would not suffice for the metabolic needs of the pregnancy at term, where high perfusion rates are critical. Thus, understanding this dramatic increase in uterine blood flow is essential for comprehending the hemodynamic changes that occur during pregnancy.